Light-activated wound healing and tissue modification | Zendy

Irene E. Kochevar | Zendy; Robert W. Redmond | Zendy

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Light-activated wound healing and tissue modification

Author(s) -

Irene E. Kochevar,

Robert W. Redmond

Publication year - 2016

Publication title -

the biochemist

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.126

H-Index - 7

eISSN - 1740-1194

pISSN - 0954-982X

DOI - 10.1042/bio03806020

Subject(s) - cornea , light therapy , ultraviolet light , laser light , macular degeneration , medicine , biomedical engineering , fluorescence , visible spectrum , wound healing , materials science , ophthalmology , laser , optics , optoelectronics , surgery , physics , circadian rhythm , endocrinology

The unique properties of light have led to the development of many effective medical treatments. Ultraviolet, visible and infrared light can be focused to small tissue volumes, providing spatial specificity for treatments. The specificity is further enhanced when a dye is applied because the light is only absorbed in the tissue volume that is stained with the dye. Light can also be delivered in a time-controlled manner by simply turning on or off a switch. Thus, in contrast to drugs, the treatment can be exquisitely tuned. Currently, light is frequently used to treat skin diseases such as psoriasis and diseases of the eye such as keratoconus (involving thinning of the cornea), age-related macular degeneration (AMD) and diabetic retinopathy, and light is used with dyes to treat certain malignancies. In addition, promising results have been reported for the destruction of pathogenic microbes by light, with and without a dye. The light sources employed range from simple fluorescent tubes to high-powered lasers.

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