Type 1 diabetes: treat the symptoms or cure the disease?
Author(s) -
Aileen King,
Zheng-liang Zhi,
Shanta J. Persaud,
Peter M. Jones
Publication year - 2016
Publication title -
the biochemist
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.126
H-Index - 7
eISSN - 1740-1194
pISSN - 0954-982X
DOI - 10.1042/bio03804005
Subject(s) - biocompatible material , islet , medicine , type 2 diabetes , disease , diabetes mellitus , transplantation , type 1 diabetes , graft versus host disease , intensive care medicine , surgery , endocrinology , biomedical engineering
Islet transplantation has shown great promise as an experimental treatment for Type 1 diabetes, but current clinical protocols have problems with long-term graft survival when islets are transplanted into an inflammatory, immunogenic host environment. Encapsulation strategies designed to present a biocompatible barrier between graft and host may offer solutions to these problems.
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