Open AccessIlluminating Xist
Author(s) -
Heather Coker,
Benoît Moindrot,
Greta Pintacuda,
Neil Brockdorff
Publication year - 2015
Publication title -
the biochemist
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.126
H-Index - 7
eISSN - 1740-1194
pISSN - 0954-982X
DOI - 10.1042/bio03702024
Subject(s) - xist , rna , computational biology , biology , long non coding rna , dna , genome , non coding rna , genetics , computer science , gene , x inactivation , x chromosome
The Central Dogma proposed that RNA, encoded by DNA in the genome, acts as the template used by cells for protein production. The simplicity of RNA as a discrete mediator of information has subsequently been challenged by the discovery of non-protein-coding RNAs. Understanding of this intricate new field has been fuelled by the development of new research techniques. In this article, we consider how recent advances in microscopy have added to our current understanding of the non-coding RNA Xist (X-inactive specific transcript).
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