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In touch: The molecular basis of mechanosensory transduction
Author(s) -
Lijun Kang,
Seth A. Wescott,
Wei Li,
X.Z. Shawn Xu
Publication year - 2011
Publication title -
the biochemist
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.126
H-Index - 7
eISSN - 1740-1194
pISSN - 0954-982X
DOI - 10.1042/bio03306018
Subject(s) - mechanosensitive channels , transduction (biophysics) , caenorhabditis elegans , drosophila melanogaster , mechanosensation , biology , electrophysiology , neuroscience , mechanotransduction , transient receptor potential channel , communication , genetics , ion channel , gene , biophysics , psychology , receptor
Nearly all species employ mechanosensitive channels to detect mechanical cues, such as touch and sound waves, and convert these mechanical forces into electrochemical signals. Genetic, biochemical and electrophysiological studies of touch-insensitive mutants in model organisms such as Caenorhabditis elegans and Drosophila melanogaster provide insights into the molecular basis of mechanosensory transduction.

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