Epigenetic mechanisms to maintain embryonic stem cell identity | Zendy

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Epigenetic mechanisms to maintain embryonic stem cell identity

Author(s) -

Sarah Cooper

Publication year - 2010

Publication title -

the biochemist

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.126

H-Index - 7

eISSN - 1740-1194

pISSN - 0954-982X

DOI - 10.1042/bio03205011

Subject(s) - embryonic stem cell , stem cell , microbiology and biotechnology , epigenetics , biology , regeneration (biology) , germ layer , neuroscience , induced pluripotent stem cell , genetics , gene

Advocates of embryonic stem (ES) cells have promised much from this technology, from reversal of neurodegenerative diseases to custom tissue regeneration. What is it, then, that makes ES cells so remarkable? Essentially, this question can be answered by two major features: an ability to self-renew and thereby divide indefinitely in culture, and pluripotency, the ability to respond to external signals and differentiate into any type of cell in the body, including germ cells.

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