Open AccessPhosphoinositides: Navigation through the endosomal maze
Author(s) -
Anna C. Rutherford,
Peter J. Cullen
Publication year - 2009
Publication title -
the biochemist
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.126
H-Index - 7
eISSN - 1740-1194
pISSN - 0954-982X
DOI - 10.1042/bio03105020
Subject(s) - endosome , intracellular , microbiology and biotechnology , membrane , signal transduction , flux (metallurgy) , signalling , cell , cell membrane , chemistry , biology , biochemistry , organic chemistry
For many years, the phosphoinositide (PI) family of membrane lipids was studied because of its importance as intermediates in signal transduction pathways. Over the last decade, it has become increasingly clear that, in addition to these signalling functions, PIs are one of the key regulators governing the identity of intracellular membranes and the flux of membrane through the cell.
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