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Is the party over: Ecstasy
Author(s) -
J. R. Morton
Publication year - 2007
Publication title -
the biochemist
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.126
H-Index - 7
eISSN - 1740-1194
pISSN - 0954-982X
DOI - 10.1042/bio02902004
Subject(s) - ecstasy , mdma , recreational drug , recreational use , recreation , neurotoxicity , medicine , pharmacology , psychiatry , psychology , drug , political science , toxicity , law
To a generation of partygoers, Ecstasy [3,4methylenedioxymethamphetamine (MDMA)] represents one of the safest illegal drugs available and, superficially, evidence supports this notion. Compared with other recreational drugs, there have been relatively few Ecstasyrelated deaths and there is little direct evidence for shortterm neurotoxicity at recreational doses. However, Ecstasy causes 5hydroxytryptamine (5HT) nerveterminal damage in rats, mice and monkeys, and, in several studies, the damage is irreversible.

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