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Traffic watch: Live-cell imaging
Author(s) -
David Stephens
Publication year - 2003
Publication title -
the biochemist
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.126
H-Index - 7
eISSN - 1740-1194
pISSN - 0954-982X
DOI - 10.1042/bio02503015
Subject(s) - coining (mint) , live cell imaging , living cell , cell function , cell , nanotechnology , microscopy , microbiology and biotechnology , computer science , biology , materials science , physics , optics , genetics , metallurgy
Microscopy has been at the core of cell biology research ever since the coining of the term ‘cell’ by Robert Hooke in the 17th Century1. For many years, it has been possible to gain insight into ‘steady-state’ cellular function from the analysis of fixed samples, but it is only relatively recently that imaging of living cells has become a widely used tool to support biochemical and electron microscopy studies. Membrane traffic research, which by its very nature is a highly dynamics process, has benefited hugely from the ability to image specific processes in living cells and tissues.

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