Open AccessPKC isoforms activate LRRK1 kinase by phosphorylating conserved residues (Ser1064, Ser1074 and Thr1075) within the CORB GTPase domain
Author(s) -
Asad Malik,
Athanasios Karapetsas,
Raja Sekhar Nirujogi,
Deep Chatterjee,
Toan K. Phung,
Melanie Wightman,
Robert Gourlay,
Nick Morrice,
Sebastian Mathea,
Stefan Knapp,
Dario R. Alessi
Publication year - 2022
Publication title -
biochemical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.706
H-Index - 265
eISSN - 1470-8728
pISSN - 0264-6021
DOI - 10.1042/bcj20220308
Subject(s) - phosphorylation , protein kinase domain , protein kinase c , kinase , lrrk2 , gtpase , biochemistry , chemistry , microbiology and biotechnology , biology , mutation , biophysics , mutant , gene
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