Open AccessMerging C–C σ-bond activation of cyclobutanones with CO2 fixation via Ni-catalysis
Author(s) -
Lorenzo Lombardi,
Alessandro Cerveri,
Leonardo Ceccon,
Riccardo Pedrazzani,
Magda Monari,
Giulio Bertuzzi,
Marco Bandini
Publication year - 2022
Publication title -
chemical communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.837
H-Index - 333
eISSN - 1364-548X
pISSN - 1359-7345
DOI - 10.1039/d2cc00149g
Subject(s) - electrophile , catalysis , chemistry , tandem , yield (engineering) , functional group , combinatorial chemistry , electrophilic addition , stereochemistry , medicinal chemistry , organic chemistry , materials science , polymer , metallurgy , composite material
A carboxylative Ni-catalyzed tandem C–C σ-bond activation of cyclobutanones followed by CO 2 -electrophilic trapping is documented as a direct route to synthetically valuable 3-indanone-1-acetic acids.