Fe/S-Catalyzed synthesis of 2-benzoylbenzoxazoles and 2-quinolylbenzoxazoles via redox condensation of o-nitrophenols with acetophenones and methylquinolines | Zendy

Le Anh Nguyen | Zendy; Thi Thu Tram Nguyen | Zendy; Quoc Anh Ngo | Zendy; Thanh Bình Nguyễn | Zendy

Open Access

Fe/S-Catalyzed synthesis of 2-benzoylbenzoxazoles and 2-quinolylbenzoxazoles via redox condensation of o-nitrophenols with acetophenones and methylquinolines

Author(s) -

Le Anh Nguyen,

Thi Thu Tram Nguyen,

Quoc Anh Ngo,

Thanh Bình Nguyễn

Publication year - 2021

Publication title -

organic and biomolecular chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.923

H-Index - 146

eISSN - 1477-0539

pISSN - 1477-0520

DOI - 10.1039/d1ob00976a

Subject(s) - chemistry , catalysis , condensation , redox , sulfur , amine gas treating , base (topology) , condensation reaction , medicinal chemistry , tertiary amine , organic chemistry , mathematical analysis , physics , mathematics , thermodynamics

An Fe/S catalyst generated in situ from FeCl 2 ·4H 2 O and elemental sulfur S 8 in the presence of a tertiary amine as a base was found to catalyze efficiently a 6e - redox condensation of o-nitrophenols with acetophenones and methylquinolines. The condensed products 2-benzoylbenzoxazoles and 2-quinolylbenzoxazoles were obtained in reasonable yields with water as the only byproduct at a temperature as low as 80 °C.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research