Enantioselective Au(i)-catalyzed dearomatization of 1-naphthols with allenamides through Tethered Counterion-Directed Catalysis | Zendy

Yunliang Yu | Zendy; Zhenhao Zhang | Zendy; Arnaud Voituriez | Zendy; Nicolas Rabasso | Zendy; Gilles Frison | Zendy; Angéla Marinetti | Zendy; Xavier Guinchard | Zendy

Open Access

Enantioselective Au(i)-catalyzed dearomatization of 1-naphthols with allenamides through Tethered Counterion-Directed Catalysis

Author(s) -

Yunliang Yu,

Zhenhao Zhang,

Arnaud Voituriez,

Nicolas Rabasso,

Gilles Frison,

Angéla Marinetti,

Xavier Guinchard

Publication year - 2021

Publication title -

chemical communications

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.837

H-Index - 333

eISSN - 1364-548X

pISSN - 1359-7345

DOI - 10.1039/d1cc04088j

Subject(s) - enantioselective synthesis , counterion , catalysis , chemistry , iminium , electrophile , intramolecular force , combinatorial chemistry , organocatalysis , synergistic catalysis , stereochemistry , organic chemistry , ion

The Tethered Counterion-Directed Catalysis (TCDC) approach has been applied to the enantioselective Au(I) catalyzed dearomatizations of 1-naphthols with allenamides. Stereocontrol is ensured by the intramolecular ion-pairing between the chiral gold-tethered phosphate and an iminium unit, that provides a rigid, well-defined chiral environment to the key electrophilic intermediate.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research