Open AccessDiscovery of quinolone derivatives as antimycobacterial agents
Author(s) -
Kun-Lin Liu,
Fei Teng,
Lu Xiong,
Xiao Li,
Chao Gao,
Luoting Yu
Publication year - 2021
Publication title -
rsc advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.746
H-Index - 148
ISSN - 2046-2069
DOI - 10.1039/d0ra09250a
Subject(s) - antimycobacterial , quinolone , solubility , cytotoxicity , chemistry , minimum inhibitory concentration , stereochemistry , medicinal chemistry , antimicrobial , mycobacterium tuberculosis , antibiotics , organic chemistry , tuberculosis , medicine , in vitro , biochemistry , pathology
6b21 : MIC against M. tb H 37 Rv = 1.2 μg mL −1 , MIC against drug-resistant strains = 0.9 μg mL −1 , solubility = 132 μg mL −1 , non-cytotoxicity.
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