Reply to the ‘Comment on “Investigation of Zr(iv) and 89Zr(iv) complexation with hydroxamates: progress towards designing a better chelator than desferrioxamine B for immuno-PET imaging”’ by A. Bianchi and M. Savastano, Chem. Commun., 2020, 56, D0CC01189D | Zendy

François Guérard | Zendy; Yong Sok Lee | Zendy; Raphaël Tripier | Zendy; Lawrence P. Szajek | Zendy; Jeffrey R. Deschamps | Zendy; Martin W. Brechbiel | Zendy

Open Access

Reply to the ‘Comment on “Investigation of Zr(iv) and ⁸⁹Zr(iv) complexation with hydroxamates: progress towards designing a better chelator than desferrioxamine B for immuno-PET imaging”’ by A. Bianchi and M. Savastano, Chem. Commun., 2020, 56, D0CC01189D

Author(s) -

François Guérard,

Yong Sok Lee,

Raphaël Tripier,

Lawrence P. Szajek,

Jeffrey R. Deschamps,

Martin W. Brechbiel

Publication year - 2020

Publication title -

chemical communications

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.837

H-Index - 333

eISSN - 1364-548X

pISSN - 1359-7345

DOI - 10.1039/d0cc03594g

Subject(s) - context (archaeology) , chelation , chemistry , medicinal chemistry , stereochemistry , inorganic chemistry , paleontology , biology

The alternative analysis of A. Bianchi and M. Savastano is a valuable contribution to the understanding of the complex systems at stake in the complexation chemistry of Zr 4+ by considering polynuclear species. Placed in the context of nuclear medicine where such aggregates are unlikely and considering recent literature data, this however points out that no clear agreement exists to describe such complex formation.

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