Intramolecularly stapled amphipathic peptidesviaa boron–sugar interaction | Zendy

Monika Kijewska | Zendy; Angelika Czerwińska | Zendy; Samah Al-Harthi | Zendy; Grzegorz Wołczański | Zendy; Mateusz Waliczek | Zendy; AbdulHamid Emwas | Zendy; Mariusz Jaremko | Zendy; Łukasz Jaremko | Zendy; Piotr Stefanowicz | Zendy; Zbigniew Szewczuk | Zendy

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Intramolecularly stapled amphipathic peptidesviaa boron–sugar interaction

Author(s) -

Monika Kijewska,

Angelika Czerwińska,

Samah Al-Harthi,

Grzegorz Wołczański,

Mateusz Waliczek,

AbdulHamid Emwas,

Mariusz Jaremko,

Łukasz Jaremko,

Piotr Stefanowicz,

Zbigniew Szewczuk

Publication year - 2020

Publication title -

chemical communications

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.837

H-Index - 333

eISSN - 1364-548X

pISSN - 1359-7345

DOI - 10.1039/d0cc02603d

Subject(s) - chemistry , intramolecular force , moiety , phenylboronic acid , circular dichroism , boron , amphiphile , peptide , mass spectrometry , nuclear magnetic resonance spectroscopy , stereochemistry , organic chemistry , biochemistry , chromatography , polymer , copolymer , catalysis

Amadori products (deoxyfructosyllysine derivatives) that can selectively interact with phenylboronic acids and borate ions were synthesized. The intramolecular interactions between the fructosyl moiety and phenylboronic acid incorporated into various positions of the peptide chain were investigated using high-resolution mass spectrometry (HR-MS), circular dichroism (CD), and nuclear magnetic resonance (NMR).

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