Open AccessDendrimer-conjugated podophyllotoxin suppresses DENA-induced HCC progression by modulation of inflammatory and fibrogenic factors
Author(s) -
Supriya Sharma,
Mehak Mehak,
Jyoti Chhimwal,
Vikram Patial,
Ugir Hossain Sk
Publication year - 2019
Publication title -
toxicology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.709
H-Index - 31
eISSN - 2045-4538
pISSN - 2045-452X
DOI - 10.1039/c9tx00103d
Subject(s) - podophyllotoxin , chemistry , conjugated system , pharmacology , toxicity , dendrimer , solubility , cancer research , medicine , biochemistry , stereochemistry , organic chemistry , polymer
Podophyllotoxin has been explored as an anticancer, antiviral, and antibacterial agent; however, its low water solubility and toxicity limit its use.
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