Nanomolar detection of adenosine triphosphate (ATP) using a nanostructured fluorescent chemosensing ensemble | Zendy

Ling-Xi Huang | Zendy; Qing Guo | Zendy; Yong Chen | Zendy; Peter Verwilst | Zendy; Subin Son | Zendy; Jia-Bin Wu | Zendy; QianYong Cao | Zendy; Jong Seung Kim | Zendy

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Nanomolar detection of adenosine triphosphate (ATP) using a nanostructured fluorescent chemosensing ensemble

Author(s) -

Ling-Xi Huang,

Qing Guo,

Yong Chen,

Peter Verwilst,

Subin Son,

Jia-Bin Wu,

QianYong Cao,

Jong Seung Kim

Publication year - 2019

Publication title -

chemical communications

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.837

H-Index - 333

eISSN - 1364-548X

pISSN - 1359-7345

DOI - 10.1039/c9cc08054f

Subject(s) - fluorescence , pyridinium , adenosine triphosphate , amphiphile , aqueous solution , detection limit , chemistry , salt (chemistry) , biophysics , combinatorial chemistry , nanotechnology , materials science , biochemistry , chromatography , organic chemistry , copolymer , biology , physics , quantum mechanics , polymer

We report a novel nanostructured chemosensing ensemble PyNp-C13/UD, obtained by self-assembling uranine dye (UD) and an amphiphilic pyridinium salt PyNp-C13. The ensemble was developed for the fluorescence turn-on sensing of ATP in aqueous solutions and inside living cells. The assembly operates via an indicator displacement assay (IDA) method with an ultra-low detection limit of 6.8 nM.

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