Open AccessEnantioselective organocatalytic activation of vinylidene–quinone methides (VQMs)
Author(s) -
Jean Rodríguez,
Damien Bonne
Publication year - 2019
Publication title -
chemical communications
Language(s) - English
Resource type - Journals
eISSN - 1364-548X
pISSN - 1359-7345
DOI - 10.1039/c9cc05097c
Subject(s) - enantioselective synthesis , electrophile , quinone , reagent , reactivity (psychology) , chirality (physics) , chemistry , organocatalysis , combinatorial chemistry , organic chemistry , phenols , catalysis , physics , medicine , chiral symmetry breaking , alternative medicine , pathology , quantum mechanics , nambu–jona lasinio model , quark
Vinylidene–quinone methides (VQMs) are highly electrophilic chiral reagents that can be generated in situ from 2-(phenylethynyl)phenols. Their specific reactivity has revealed innovative strategies notably for the control of axial chirality.