Capsaicin enhances erlotinib-induced cytotoxicity via AKT inactivation and excision repair cross-complementary 1 (ERCC1) down-regulation in human lung cancer cells
Author(s) -
JyhCheng Chen,
JenChung Ko,
Ting-Chuan Yen,
TzuYing Chen,
Yuan-Cheng Lin,
Peng-Fang Ma,
YunWei Lin
Publication year - 2019
Publication title -
toxicology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.709
H-Index - 31
eISSN - 2045-4538
pISSN - 2045-452X
DOI - 10.1039/c8tx00346g
Subject(s) - capsaicin , ercc1 , erlotinib , cytotoxicity , lung cancer , pharmacology , cancer research , ingredient , cisplatin , medicine , chemistry , cancer , nucleotide excision repair , chemotherapy , biochemistry , oncology , in vitro , receptor , food science , epidermal growth factor receptor , dna repair , gene
Capsaicin, a natural active ingredient of green and red peppers, has been demonstrated to exhibit anti-cancer properties in several malignant cell lines.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom