Clusterin increases mitochondrial respiratory chain complex I activity and protects against hexavalent chromium-induced cytotoxicity in L-02 hepatocytes | Zendy

Yuanyuan Xiao | Zendy; Ming Zeng | Zendy; Lirong Yin | Zendy; Na Li | Zendy; Fang Xiao | Zendy

Open Access

Clusterin increases mitochondrial respiratory chain complex I activity and protects against hexavalent chromium-induced cytotoxicity in L-02 hepatocytes

Author(s) -

Yuanyuan Xiao,

Ming Zeng,

Lirong Yin,

Na Li,

Fang Xiao

Publication year - 2018

Publication title -

toxicology research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.709

H-Index - 31

eISSN - 2045-4538

pISSN - 2045-452X

DOI - 10.1039/c8tx00231b

Subject(s) - hexavalent chromium , cytotoxicity , mitochondrial respiratory chain , clusterin , respiratory chain , mitochondrion , chemistry , chromium , reactive oxygen species , biochemistry , apoptosis , in vitro , organic chemistry

Previous evidence revealed significant elevated liver cancer mortality in the areas where water was contaminated with hexavalent chromium [Cr( vi )], which highlighted that we should pay more attention to Cr( vi )-induced cytotoxicity in hepatocytes.

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