Chronic low-level cadmium exposure in rats affects cytokine production by activated T cells | Zendy

Alexandra E. Turley | Zendy; Joseph Zagorski | Zendy; Rebekah C. Kennedy | Zendy; Robert A. Freeborn | Zendy; Jenna K. Bursley | Zendy; Joshua R. Edwards | Zendy; Cheryl E. Rockwell | Zendy

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Chronic low-level cadmium exposure in rats affects cytokine production by activated T cells

Author(s) -

Alexandra E. Turley,

Joseph Zagorski,

Rebekah C. Kennedy,

Robert A. Freeborn,

Jenna K. Bursley,

Joshua R. Edwards,

Cheryl E. Rockwell

Publication year - 2019

Publication title -

toxicology research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.709

H-Index - 31

eISSN - 2045-4538

pISSN - 2045-452X

DOI - 10.1039/c8tx00194d

Subject(s) - cadmium , cadmium exposure , cytokine , ex vivo , immune system , in vivo , medicine , immunology , toxicology , physiology , andrology , chemistry , biology , microbiology and biotechnology , organic chemistry

The purpose of this study was to determine the effect of subchronic, oral, low-dose cadmium exposure (32 ppm over 10 weeks) on the rat immune system. We found that cadmium exposure increased the induction of IFNγ and IL-10 in T cells activated ex vivo after cadmium exposure.

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