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The mitochondrial pathway is involved in sodium fluoride (NaF)-induced renal apoptosis in mice
Author(s) -
Wei Qin,
Qin Luo,
Huan Liu,
Linlin Chen,
Hengmin Cui,
Jing Fang,
Zhicai Zuo,
Junliang Deng,
Yinglun Li,
Xun Wang,
Ling Zhao
Publication year - 2018
Publication title -
toxicology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.709
H-Index - 31
eISSN - 2045-4538
pISSN - 2045-452X
DOI - 10.1039/c8tx00130h
Subject(s) - sodium fluoride , apoptosis , fluoride , mitochondrion , chemistry , sodium , pharmacology , medicine , endocrinology , biochemistry , inorganic chemistry , organic chemistry
The objective of the present study was to explore the molecular mechanism of apoptosis induced by sodium fluoride (NaF) in the mouse kidney by using the methods of flow cytometry, quantitative real-time polymerase chain reaction (qRT-PCR), western blotting, and experimental pathology.

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