Open AccessRoles of ERK1/2 and PI3K/AKT signaling pathways in mitochondria-mediated apoptosis in testes of hypothyroid rats
Author(s) -
Yueli Yao,
Xiaoru Chang,
Dong Wang,
Haitao Ma,
Huiling Wang,
Haojun Zhang,
Chengyun Li,
Junling Wang
Publication year - 2018
Publication title -
toxicology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.709
H-Index - 31
eISSN - 2045-4538
pISSN - 2045-452X
DOI - 10.1039/c8tx00122g
Subject(s) - apoptosis , pi3k/akt/mtor pathway , mitochondrion , mechanism (biology) , protein kinase b , endocrinology , hormone , medicine , microbiology and biotechnology , signal transduction , function (biology) , thyroid , biology , chemistry , genetics , physics , quantum mechanics
The absence of the thyroid hormone (TH) could impair testicular function, but its mechanism is still rudimentary.
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