An in vitro method for nephrotoxicity evaluation using HK-2 human kidney epithelial cells combined with biomarkers of nephrotoxicity
Author(s) -
Xuan Qiu,
Xiaobing Zhou,
Yufa Miao,
Bo Li
Publication year - 2018
Publication title -
toxicology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.709
H-Index - 31
eISSN - 2045-4538
pISSN - 2045-452X
DOI - 10.1039/c8tx00095f
Subject(s) - nephrotoxicity , in vitro , kidney , human kidney , medicine , pharmacology , urology , chemistry , biochemistry
The HK-2 cell model based on clusterin, osteopontin, CysC and KIM-1 would allow the prediction of nephrotoxicity at early stages.
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