Open AccessAmino-PAHs activated Nrf2/ARE anti-oxidative defense system and promoted inflammatory responses: the regulation of PI3K/Akt pathway
Author(s) -
Meiying Wu,
Yuting Jiang,
Mingyuan Liu,
Yu Shang,
Jing An
Publication year - 2018
Publication title -
toxicology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.709
H-Index - 31
eISSN - 2045-4538
pISSN - 2045-452X
DOI - 10.1039/c8tx00010g
Subject(s) - pi3k/akt/mtor pathway , protein kinase b , oxidative phosphorylation , microbiology and biotechnology , oxidative stress , signal transduction , chemistry , inflammation , cancer research , biochemistry , biology , immunology
The amino polycyclic aromatic hydrocarbons (amino-PAHs) were frequently detected in PM 2.5 , and it was suggested that they contributed to the harmful health effects associated with PM 2.5 .
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