Open AccessCorrelation of the cytotoxic effects of cationic lipids with their headgroups
Author(s) -
Shaohui Cui,
Yueying Wang,
Yan Gong,
Xiao Lin,
Yinan Zhao,
Defu Zhi,
Quan Zhou,
Shubiao Zhang
Publication year - 2018
Publication title -
toxicology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.709
H-Index - 31
eISSN - 2045-4538
pISSN - 2045-452X
DOI - 10.1039/c8tx00005k
Subject(s) - cationic polymerization , cytotoxic t cell , toxicity , chemistry , genetic enhancement , computational biology , biology , gene , biochemistry , in vitro , organic chemistry
As effective non-viral vectors of gene therapy, cationic lipids still have the problem of toxicity, which has become one of the main bottlenecks for their applications.
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