Opto-acousto-fluidic microscopy for three-dimensional label-free detection of droplets and cells in microchannels | Zendy

Chaolong Song | Zendy; Tian Jin | Zendy; Ruopeng Yan | Zendy; Weizhi Qi | Zendy; Tianye Huang | Zendy; Huafeng Ding | Zendy; Say Hwa Tan | Zendy; NamTrung Nguyen | Zendy; Lei Xi | Zendy

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Opto-acousto-fluidic microscopy for three-dimensional label-free detection of droplets and cells in microchannels

Author(s) -

Chaolong Song,

Tian Jin,

Ruopeng Yan,

Weizhi Qi,

Tianye Huang,

Huafeng Ding,

Say Hwa Tan,

NamTrung Nguyen,

Lei Xi

Publication year - 2018

Publication title -

lab on a chip

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.064

H-Index - 210

eISSN - 1473-0197

pISSN - 1473-0189

DOI - 10.1039/c8lc00106e

Subject(s) - microfluidics , fluidics , microscopy , materials science , absorbance , nanotechnology , optical microscope , chemistry , optics , chromatography , scanning electron microscope , physics , composite material , aerospace engineering , engineering

This paper reports a novel method, opto-acousto-fluidic microscopy, for label-free detection of droplets and cells in microfluidic networks. Leveraging the optoacoustic effect, the microscopic system possesses capabilities of visualizing flowing droplets, analyzing droplet contents, and detecting cell populations encapsulated in droplets via the sensing of acoustic waves induced by the intrinsic light-absorbance of matter.

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