Mechanisms of action of Ru(ii) polypyridyl complexes in living cells upon light irradiation | Zendy

Marta Jakubaszek | Zendy; Bruno Goud | Zendy; Stefano Ferrari | Zendy; Gilles Gasser | Zendy

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Mechanisms of action of Ru(ii) polypyridyl complexes in living cells upon light irradiation

Author(s) -

Marta Jakubaszek,

Bruno Goud,

Stefano Ferrari,

Gilles Gasser

Publication year - 2018

Publication title -

chemical communications

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.837

H-Index - 333

eISSN - 1364-548X

pISSN - 1359-7345

DOI - 10.1039/c8cc05928d

Subject(s) - irradiation , photodynamic therapy , chemistry , mechanism of action , action (physics) , combinatorial chemistry , ruthenium , photochemistry , biophysics , biochemistry , catalysis , biology , organic chemistry , physics , in vitro , quantum mechanics , nuclear physics

The unique photophysical properties of Ru(ii) polypyridyl complexes make them very attractive candidates as photosensitisers in Photodynamic Therapy (PDT). However, to date, there are not many studies exploring in detail the mechanism(s) of action of such compounds in living systems upon light irradiation. This feature article provides an overview of the most in-depth biological studies on such compounds.

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