Open AccessTributylphosphate (TBP) and tris (2-butoxyethyl) phosphate (TBEP) induced apoptosis and cell cycle arrest in HepG2 cells
Author(s) -
Guofa Ren,
Jingwen Hu,
Yu Shang,
Yufang Zhong,
Zhiqiang Yu,
Jing An
Publication year - 2017
Publication title -
toxicology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.709
H-Index - 31
eISSN - 2045-4538
pISSN - 2045-452X
DOI - 10.1039/c7tx00180k
Subject(s) - tris , apoptosis , cell cycle checkpoint , oxidative stress , phosphate , chemistry , cell cycle , oxidative phosphorylation , pharmacology , biochemistry , biology
The purpose of this study was to investigate the cytotoxic effects of tributylphosphate (TBP) and tris (2-butoxyethyl) phosphate (TBEP) and to explore the underlying molecular mechanism focusing on oxidative stress, apoptosis, and cell cycle arrest.
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