MicroRNA-29b inhibits supernatants from silica-treated macrophages from inducing extracellular matrix synthesis in lung fibroblasts | Zendy

Ximeng Lian | Zendy; Xiaowei Chen | Zendy; Jingping Sun | Zendy; Guoliang An | Zendy; Xiaoli Li | Zendy; Yan Wang | Zendy; Piye Niu | Zendy; Zhonghui Zhu | Zendy; Lin Tian | Zendy

Open Access

MicroRNA-29b inhibits supernatants from silica-treated macrophages from inducing extracellular matrix synthesis in lung fibroblasts

Author(s) -

Ximeng Lian,

Xiaowei Chen,

Jingping Sun,

Guoliang An,

Xiaoli Li,

Yan Wang,

Piye Niu,

Zhonghui Zhu,

Lin Tian

Publication year - 2017

Publication title -

toxicology research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.709

H-Index - 31

eISSN - 2045-4538

pISSN - 2045-452X

DOI - 10.1039/c7tx00126f

Subject(s) - extracellular matrix , extracellular , fibroblast , microbiology and biotechnology , lung , chemistry , microrna , matrix (chemical analysis) , macrophage , cancer research , biochemistry , biology , medicine , in vitro , gene , chromatography

Supernatants from silica-treated macrophages induced the lung fibroblasts proliferation, miR-29b reduced and extracellular matrix synthesis increased, which could be markedly inhibited by overexpression of miR-29b.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research