Open AccessToxicological implications of mitochondrial localization of CYP2E1
Author(s) -
Jessica H. Hartman,
Grover P. Miller,
Joel N. Meyer
Publication year - 2017
Publication title -
toxicology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.709
H-Index - 31
eISSN - 2045-4538
pISSN - 2045-452X
DOI - 10.1039/c7tx00020k
Subject(s) - cyp2e1 , mitochondrial dna , mitochondrion , biology , computational biology , genetics , gene , biochemistry , metabolism , cytochrome p450
This review discusses links between mitochondria-localized cytochrome P450 2E1 (CYP2E1) and toxicity, particularly mitochondrial dysfunction, and poses open questions in this emerging field.
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