Open AccessCigarette smoke extract induces the epithelial-to-mesenchymal transition via the PLTP/TGF-β1/Smad2 pathway in RLE-6TN cells
Author(s) -
Hong Chen,
Fengping Wu,
Yongzhen Yang,
Xiuying Yu,
Lu Zhang,
Hui Zhang,
Yajuan Chen
Publication year - 2016
Publication title -
toxicology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.709
H-Index - 31
eISSN - 2045-4538
pISSN - 2045-452X
DOI - 10.1039/c6tx00378h
Subject(s) - epithelial–mesenchymal transition , downregulation and upregulation , microbiology and biotechnology , cigarette smoke , transforming growth factor , chemistry , mesenchymal stem cell , biology , biochemistry , gene , toxicology
Aim : The role of phospholipid transfer protein (PLTP) in the pathogenesis of the cigarette smoke extract (CSE)-induced epithelial-to-mesenchymal transition (EMT) has not been well described.
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