Open AccessApplication research on PPARα-transgenic mice in preclinical safety evaluation of gemfibrozil
Author(s) -
Yan Li,
Hongmei Mao,
Yanfeng Xu,
Xiaocen Li,
Pan Lishan,
Xin Wu,
Yang Li,
Yi Li,
Jun He
Publication year - 2016
Publication title -
toxicology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.709
H-Index - 31
eISSN - 2045-4538
pISSN - 2045-452X
DOI - 10.1039/c6tx00271d
Subject(s) - gemfibrozil , genetically modified mouse , peroxisome proliferator activated receptor , body weight , medicine , endocrinology , hepatocyte , muscle hypertrophy , incidence (geometry) , transgene , receptor , chemistry , biochemistry , cholesterol , gene , physics , optics , in vitro
PPARα-transgenic mice could serve as a useful tool for preclinical safety evaluation of gemfibrozil.
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