Open AccessPyrazinamide-induced hepatotoxicity and gender differences in rats as revealed by a1H NMR based metabolomics approach
Author(s) -
He Zhao,
Zhi-Hong Si,
Minghui Li,
Lei Jiang,
Yong-Hong Fu,
Yue-Xiao Xing,
Hong Wei,
Ling-Yu Ruan,
Pu-Ming Li,
Junsong Wang
Publication year - 2016
Publication title -
toxicology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.709
H-Index - 31
eISSN - 2045-4538
pISSN - 2045-452X
DOI - 10.1039/c6tx00245e
Subject(s) - metabolomics , pyrazinamide , medicine , chemistry , pharmacology , chromatography , pathology , isoniazid , tuberculosis
Pyrazinamide disturbed the metabolic profiles of rats with gender difference, with regard to metabolic pathways related to its hepatotoxicity.
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