Open AccessSilica nanoparticles induce start inhibition of meiosis and cell cycle arrest via down-regulating meiotic relevant factors
Author(s) -
Jin Zhang,
Lihua Ren,
Yang Zou,
Lianshuang Zhang,
Jialiu Wei,
Yanbo Li,
Ji Wang,
Zhiwei Sun,
Xianqing Zhou
Publication year - 2016
Publication title -
toxicology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.709
H-Index - 31
eISSN - 2045-4538
pISSN - 2045-452X
DOI - 10.1039/c6tx00236f
Subject(s) - meiosis , cell cycle checkpoint , microbiology and biotechnology , oxidative stress , cell cycle , chemistry , cell , biology , gene , biochemistry
Silica nanoparticles induced cell cycle arrest and proliferation inhibition by down-regulating the expressions of meiotic regulatory factors through causing DNA damages resulting from oxidative stress, leading to the inhibition of the start and process of meiosis.
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