Open AccessEffects of multi-component mixtures of polyaromatic hydrocarbons and heavy metal/loid(s) on Nrf2-antioxidant response element (ARE) pathway in ARE reporter-HepG2 cells
Author(s) -
Sasikumar Muthusamy,
Cheng Peng,
J. C. Ng
Publication year - 2016
Publication title -
toxicology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.709
H-Index - 31
eISSN - 2045-4538
pISSN - 2045-452X
DOI - 10.1039/c6tx00024j
Subject(s) - antioxidant , oxidative stress , chemistry , metal , heavy metals , environmental chemistry , organic chemistry , biochemistry
The effect of mixtures of PAHs and heavy metal/loid(s) on the Nrf2 antioxidant pathway in HepG2-ARE cells was determined as an indicator of the oxidative stress response.
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