Open AccessSynthesis and antiproliferative activity of new tonantzitlolone-derived diterpene derivatives
Author(s) -
Torsten Busch,
Gerald Dräger,
Eike Kunst,
Hannah Benson,
Florenz Sasse,
Karsten Siems,
Andreas Kirschning
Publication year - 2016
Publication title -
organic and biomolecular chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.923
H-Index - 146
eISSN - 1477-0539
pISSN - 1477-0520
DOI - 10.1039/c6ob01697a
Subject(s) - diterpene , chemistry , terpene , stereochemistry , combinatorial chemistry
The synthesis of the diterpene (+)-tonantzitlolone A and a series of derivatives is reported. The study includes the determination of their antiproliferative activities against selected cancer cell lines.
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