Valproic acid causes radiosensitivity of breast cancer cells via disrupting the DNA repair pathway | Zendy

Yue Luo | Zendy; Hui Wang | Zendy; Xipeng Zhao | Zendy; Chao Dong | Zendy; Fengmei Zhang | Zendy; Gang Guo | Zendy; Gongshe Guo | Zendy; Xiaowei Wang | Zendy; Simon N. Powell | Zendy; Zhihui Feng | Zendy

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Valproic acid causes radiosensitivity of breast cancer cells via disrupting the DNA repair pathway

Author(s) -

Yue Luo,

Hui Wang,

Xipeng Zhao,

Chao Dong,

Fengmei Zhang,

Gang Guo,

Gongshe Guo,

Xiaowei Wang,

Simon N. Powell,

Zhihui Feng

Publication year - 2016

Publication title -

toxicology research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.709

H-Index - 31

eISSN - 2045-4538

pISSN - 2045-452X

DOI - 10.1039/c5tx00476d

Subject(s) - valproic acid , histone deacetylase , radiosensitivity , dna repair , histone deacetylase inhibitor , histone , cancer research , medicine , breast cancer , pharmacology , dna damage , epilepsy , cancer , chemistry , dna , biochemistry , radiation therapy , psychiatry

Valproic acid (VPA) is one of the representative compounds of histone deacetylase inhibitors (HDACis) and is used widely for the clinical treatment of epilepsy and other convulsive diseases.

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