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Silica induced EMT and decreased the expression of BMP-7  in vivo  and  in vitro , while exogenous BMP-7 promoted MET and inhibited silica-induced EMT associated with inhibition of the p38 MAPK/transcription factor (TF) signaling pathway in RLE-6TN cells.

Bone morphogenetic protein-7 prevented epithelial-mesenchymal transition in RLE-6TN cells