Bone morphogenetic protein-7 prevented epithelial-mesenchymal transition in RLE-6TN cells | Zendy

Yan Wang | Zendy; Di Liang | Zendy; Zhonghui Zhu | Zendy; Xiaoli Li | Zendy; Guoliang An | Zendy; Piye Niu | Zendy; Li Chen | Zendy; Lin Tian | Zendy

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Bone morphogenetic protein-7 prevented epithelial-mesenchymal transition in RLE-6TN cells

Author(s) -

Yan Wang,

Di Liang,

Zhonghui Zhu,

Xiaoli Li,

Guoliang An,

Piye Niu,

Li Chen,

Lin Tian

Publication year - 2016

Publication title -

toxicology research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.709

H-Index - 31

eISSN - 2045-4538

pISSN - 2045-452X

DOI - 10.1039/c5tx00471c

Subject(s) - microbiology and biotechnology , epithelial–mesenchymal transition , transcription factor , mesenchymal stem cell , in vivo , in vitro , bone morphogenetic protein , p38 mitogen activated protein kinases , chemistry , biology , mapk/erk pathway , transcription (linguistics) , downregulation and upregulation , bone morphogenetic protein 2 , signal transduction , gene , biochemistry , genetics , linguistics , philosophy

Silica induced EMT and decreased the expression of BMP-7 in vivo and in vitro , while exogenous BMP-7 promoted MET and inhibited silica-induced EMT associated with inhibition of the p38 MAPK/transcription factor (TF) signaling pathway in RLE-6TN cells.

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