Open AccessDiallyl trisulfide protects the liver against hepatotoxicity induced by isoniazid and rifampin in mice by reducing oxidative stress and activating Kupffer cells
Author(s) -
Yilin Yang,
Lulu Jiang,
Shuo Wang,
Tao Zeng,
Keqin Xie
Publication year - 2016
Publication title -
toxicology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.709
H-Index - 31
eISSN - 2045-4538
pISSN - 2045-452X
DOI - 10.1039/c5tx00440c
Subject(s) - isoniazid , diallyl trisulfide , oxidative stress , rifampicin , pharmacology , chemistry , medicine , microbiology and biotechnology , biochemistry , antibiotics , biology , apoptosis , tuberculosis , pathology
Diallyl trisulfide (DATS) has been verified to ameliorate hepatotoxicity induced by many drugs, but the protective actions of isoniazid (INH) and rifampicin (RFP) have not been reported.
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