Open Access1H NMR-based urine metabolomics for the evaluation of kidney injury in Wistar rats by 3-MCPD
Author(s) -
Jian Ji,
Lijuan Zhang,
Hongxia Zhang,
Chao Sun,
Jiadi Sun,
Hui Jiang,
Mandour H. Abdalhai,
YinZhi Zhang,
Xiulan Sun
Publication year - 2016
Publication title -
toxicology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.709
H-Index - 31
eISSN - 2045-4538
pISSN - 2045-452X
DOI - 10.1039/c5tx00399g
Subject(s) - metabolomics , toxicity , taurine , urine , pharmacology , chemistry , metabolism , hypotaurine , kidney , biochemistry , biology , chromatography , amino acid , endocrinology , organic chemistry
The cause of toxicity induced by 3-chloro-1,2-propanediol (3-MCPD) remains under investigation, and progress towards understanding this toxicity has been limited by the lack of sensitive and reliable biomarkers.
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