Open AccessThe acute hepatotoxicity of tacrine explained by1H NMR based metabolomic profiling
Author(s) -
Yanhong Lou,
Junsong Wang,
Ge Dong,
Pingping Guo,
Dandan Wei,
SaiSai Xie,
MingHua Yang,
Lingyi Kong
Publication year - 2015
Publication title -
toxicology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.709
H-Index - 31
eISSN - 2045-4538
pISSN - 2045-452X
DOI - 10.1039/c5tx00096c
Subject(s) - tacrine , metabolomics , chemistry , carbon 13 nmr , profiling (computer programming) , pharmacology , medicine , stereochemistry , biochemistry , chromatography , enzyme , computer science , acetylcholinesterase , operating system
NMR based metabolomics approach was applied to study the mechanism of tacrine-induced acute hepatotoxicity and had found significant disturbances.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom