Open AccessCpG site-specific RASSF1a hypermethylation is associated with occupational PAH exposure and genomic instability
Author(s) -
Zhini He,
Huawei Duan,
Biao Zhang,
Miao Li,
Liping Chen,
Bo Zhang,
Xiaonian Zhu,
Chen Gao,
Jie Li,
Xiao Zhang,
Jingmaio Zhang,
Shan Wang,
XiaoWen Zeng,
Daochuan Li,
Xiumei Xing,
Zhengbao Zhang,
Lu Ma,
Qing Bai,
Caixia Liu,
Yongmei Xiao,
Yuxin Zheng,
Wen Chen
Publication year - 2015
Publication title -
toxicology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.709
H-Index - 31
eISSN - 2045-4538
pISSN - 2045-452X
DOI - 10.1039/c5tx00013k
Subject(s) - genome instability , cpg site , dna methylation , lung cancer , cancer research , genomic dna , biology , medicine , dna damage , oncology , genetics , dna , gene , gene expression
Previous studies have shown an etiologic link between exposure to PAHs and lung cancer development.
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