Differential effects of p38 and JNK activation by GSK3 on cadmium-induced autophagy and apoptosis
Author(s) -
Ki Tae Jung,
Hak-Ryul Kim,
ByungHoon Lee,
Seong-Hwan Kim,
Keum-Young So,
Tae-Hun An,
Hyun Young Lee,
SeonHee Oh
Publication year - 2015
Publication title -
toxicology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.709
H-Index - 31
eISSN - 2045-4538
pISSN - 2045-452X
DOI - 10.1039/c5tx00007f
Subject(s) - autophagy , p38 mitogen activated protein kinases , apoptosis , cadmium , microbiology and biotechnology , differential (mechanical device) , chemistry , cancer research , biology , materials science , engineering , signal transduction , biochemistry , metallurgy , mapk/erk pathway , aerospace engineering
A proposed schematic model of the roles of p38 and JNK MAPK activation in the regulation of Cd-induced autophagy through site-specific phosphorylation in serine and tyrosine residues of GSK3αβ.
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