p,p′-Dichlorodiphenyltrichloroethane inhibits the apoptosis of colorectal adenocarcinoma DLD1 cells through PI3K/AKT and Hedgehog/Gli1 signaling pathways | Zendy

Li Song | Zendy; Meirong Zhao | Zendy; Jianxin Liu | Zendy; Zhuoyu Li | Zendy; Hong Xiao | Zendy; Weiping Liu | Zendy

Open Access

p,p′-Dichlorodiphenyltrichloroethane inhibits the apoptosis of colorectal adenocarcinoma DLD1 cells through PI3K/AKT and Hedgehog/Gli1 signaling pathways

Author(s) -

Li Song,

Meirong Zhao,

Jianxin Liu,

Zhuoyu Li,

Hong Xiao,

Weiping Liu

Publication year - 2015

Publication title -

toxicology research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.709

H-Index - 31

eISSN - 2045-4538

pISSN - 2045-452X

DOI - 10.1039/c5tx00006h

Subject(s) - gli1 , apoptosis , pi3k/akt/mtor pathway , colorectal cancer , cancer research , colorectal adenocarcinoma , hedgehog signaling pathway , adenocarcinoma , colon adenocarcinoma , hedgehog , signal transduction , protein kinase b , medicine , chemistry , oncology , biology , microbiology and biotechnology , cancer , biochemistry

p , p ′-Dichlorodiphenyltrichloroethane is able to inhibit the apoptosis of human colorectal adenocarcinoma cells, which may be an important mechanism to contribute to colorectal cancer development.

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