Tailoring biomaterial surface properties to modulate host-implant interactions: implication in cardiovascular and bone therapy | Zendy

Settimio Pacelli | Zendy; Vijayan Manoharan | Zendy; Anna Desalvo | Zendy; Nikita Lomis | Zendy; Kartikeya Singh Jodha | Zendy; Satya Prakash | Zendy; Arghya Paul | Zendy

Open Access

Tailoring biomaterial surface properties to modulate host-implant interactions: implication in cardiovascular and bone therapy

Author(s) -

Settimio Pacelli,

Vijayan Manoharan,

Anna Desalvo,

Nikita Lomis,

Kartikeya Singh Jodha,

Satya Prakash,

Arghya Paul

Publication year - 2015

Publication title -

journal of materials chemistry b

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.316

H-Index - 101

eISSN - 2050-7518

pISSN - 2050-750X

DOI - 10.1039/c5tb01686j

Subject(s) - biomaterial , materials science , implant , host (biology) , surface modification , nanotechnology , biomedical engineering , medicine , engineering , chemical engineering , surgery , biology , ecology

Host body response to a foreign medical device plays a critical role in defining its fate post implantation. It is thus important to control host-material interactions by designing innovative implant surfaces. In the recent years, biochemical and topographical features have been explored as main target to produce this new type of bioinert or bioresponsive implants. The review discusses specific biofunctional materials and strategies to achieve a precise control over implant surface properties and presents possible solutions to develop next generation of implants, particularly in the fields of bone and cardiovascular therapy.

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