Diastereoselective synthesis of fused oxazolidines and highly substituted 1H-pyrrolo [2,1-c][1,4] oxazines via C–H functionalization | Zendy

Chottanahalli S. Pavan Kumar | Zendy; Kachigere B. Harsha | Zendy; Kempegowda Mantelingu | Zendy; Kanchugarakoppal S. Rangappa | Zendy

Open Access

Diastereoselective synthesis of fused oxazolidines and highly substituted 1H-pyrrolo [2,1-c][1,4] oxazines via C–H functionalization

Author(s) -

Chottanahalli S. Pavan Kumar,

Kachigere B. Harsha,

Kempegowda Mantelingu,

Kanchugarakoppal S. Rangappa

Publication year - 2015

Publication title -

rsc advances

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.746

H-Index - 148

ISSN - 2046-2069

DOI - 10.1039/c5ra10030e

Subject(s) - surface modification , isoquinoline , chemistry , oxazines , benzoic acid , combinatorial chemistry , stereochemistry , organic chemistry

The first one pot protocol for the diastereoselective synthesis of oxazolo[2,3-c]isoquinoline was achieved by a metal-free, benzoic acid catalyzed reaction of 1,2,3,4-tetrahydroisoquinoline or trypoline with aldehydes under mild conditions via C-H, C-O bond functionalization. A new approach for the synthesis of highly substituted 1H-pyrrolo[2,1-c][1,4]oxazine was carried out

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