Open AccessGold(i ) operational in synergistic catalysis for the intermolecular α-addition reaction of aldehydes across allenamides
Author(s) -
Alberto Ballesteros,
Pablo MoránPoladura,
José M. González
Publication year - 2016
Publication title -
chemical communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.837
H-Index - 333
eISSN - 1364-548X
pISSN - 1359-7345
DOI - 10.1039/c5cc09529h
Subject(s) - intermolecular force , catalysis , chemistry , combinatorial chemistry , organic chemistry , molecule
The intermolecular reaction of allenamides with aldehydes is reported. The designed approach relies on gold(i) and organocatalysis for activating the allenamides and the aldehydes respectively. Conditions to achieve an enantioselective version of this intermolecular reaction are defined.
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