Open AccessTowards the development of mechanism-based biomarkers to diagnose drug hypersensitivity
Author(s) -
Noé DuránFigueroa,
Jesús Agustín Badillo-Corona,
Dean J. Naisbitt,
José Luis Castrejón-Flores
Publication year - 2015
Publication title -
toxicology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.709
H-Index - 31
eISSN - 2045-4538
pISSN - 2045-452X
DOI - 10.1039/c4tx00238e
Subject(s) - hapten , drug , mechanism (biology) , drug development , medicine , pharmacology , immunology , antibody , philosophy , epistemology
T-cells are activated by different mechanisms in the presence of drugs, metabolites or haptens, and they release several molecules that can be used in the diagnosis of drug hypersensitivity.
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