The Zishen Yutai pill shows no reproductive toxicity on embryo-fetal development in rats and rabbits | Zendy

Jie Zhou | Zendy; Li Zhou | Zendy; Liming Chong | Zendy; Zhonghui Wang | Zendy; Qiuling Huang | Zendy; Yubing Wu | Zendy; Yang Yang | Zendy; Aicui Ma | Zendy; Rong Wang | Zendy; Juan Jiang | Zendy; Dawei Yan | Zendy; Zuyue Sun | Zendy

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The Zishen Yutai pill shows no reproductive toxicity on embryo-fetal development in rats and rabbits

Author(s) -

Jie Zhou,

Li Zhou,

Liming Chong,

Zhonghui Wang,

Qiuling Huang,

Yubing Wu,

Yang Yang,

Aicui Ma,

Rong Wang,

Juan Jiang,

Dawei Yan,

Zuyue Sun

Publication year - 2015

Publication title -

toxicology research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.709

H-Index - 31

eISSN - 2045-4538

pISSN - 2045-452X

DOI - 10.1039/c4tx00145a

Subject(s) - toxicity , pill , reproductive toxicity , fetus , pregnancy , embryo , medicine , physiology , pharmacology , andrology , toxicology , biology , genetics , microbiology and biotechnology

High dose of Zishen Yutai pill (ZYP) showed mild maternal toxicity in rat (24 g kg −1 d −1 , 96× clinical dose) and no reproductive toxicity in rabbit (6 g kg −1 d −1 , 24× clinical dose). ZYP could be safely used at the clinical dose during pregnancy.

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